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In about 17,600 adults with obesity and established cardiovascular disease but no diabetes, semaglutide cut major cardiovascular events by 20% over roughly 40 months. This is a secondary-prevention result in people who already had heart disease

This absence of foundational pharmacokinetic information constitutes a major knowledge gap with direct implications for clinical application, dosing strategies, and safety monitoring

Despite these challenges, the potential of BPC 157 as a therapeutic agent remains significant