The combination is synergistic
This usually occurs in individuals with underlying digestive conditions, those who have trouble absorbing all nutrients through digestion, or those with pernicious anemia, which specifically prevents B12 absorption
When B12 levels become problematic: High-dose supplementation (particularly doses exceeding 1,000 micrograms daily) Frequent B12 injections without medical supervision Underlying conditions affecting B12 metabolism Concurrent use of multiple B12-containing supplements The NHS does not set an upper safe limit for vitamin B12 because harmful effects from excessive intake have not been definitively established
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What is vitamin B12 and why it matters Vitamin B12, or cobalamin, is an essential water-soluble vitamin involved in red blood cell formation, nerve health, and DNA synthesis
The answer can be unclear, especially if you have a supply