It is indirectly responsible for stimulating GLP-1 secretion
Heres the part I find most exciting, and the most underused in rheumatology right now
If you and your clinician decide to stop, the practical approach is: Step down through the available dose levels at 4-week intervals (12 mg 9 mg 6 mg 4 mg 2 mg off) rather than stopping abruptly
GLP-1 (Glucagon-Like Peptide-1) receptor agonists , such as semaglutide and tirzepatide , are FDA-approved medications designed to: Reduce appetite and hunger Increase feelings of fullness and satisfaction Improve your bodys natural insulin response Slow stomach emptying to help prevent overeating GLP-1 medications mimic natural hormone activity , helping your body re-learn healthy appetite cues and supporting significant weight loss
What are GLP-1 medications and how do they work
This dual action helps normalize blood glucose levels without causing significant hypoglycemia in most patients, though the risk increases when combined with insulin or sulfonylureas
