The body tightly regulates vitamin levels, and excess water-soluble vitamins like B12 are typically excreted in urine
J Inflamm (Lond
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Williams TL, Verdon G, Kuc RE et al (2024) Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor
"From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management." Int J Mol Sci
describe how these mechanisms are increasingly linked to the metabolic-inflammatory axis of OA, offering future therapeutic targets beyond conventional anti-inflammatories (Wu et al., 2025)