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Studies support that intracellular sodium and calcium overload induce signaling cascades that lead to dysregulation of mitochondrial homeostasis, with energy impairment and elevated free radical production, and consequent increase in cardiac hypertrophy and remodeling (Bay et al., 2013)

Eli Lilly argued that deposition testimony and post-report notes suggested plaintiffs planned to introduce previously undisclosed opinions related to gastrointestinal injuries and warning adequacy

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