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Fortunately for light-skinned individuals who want to get darker without risking damage to their skin, the MT-II peptide binds directly to the melanocortin 1 receptor on melanocytes and stimulates increased production of the darker, more photoprotective eumalanin, thus producing increased pigment and protecting skin without the need for sun exposure [4, 5, 7]

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Thus, this modest increase in LDL-C may be misleading regarding ASCVD risk, as patients with obesity may have a higher concentration of atherogenic small, dense LDL particles, and therefore high levels of apoB for a given blood LDL-C [10, 13]