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GLP-1 receptor agonist medications mimic and amplify this hormones effects, binding to receptors throughout the brain, gut, and pancreas

A landmark 2011 trial followed patients given 300 mg of ALA daily for 8 weeks and observed highly significant decreases in fasting blood glucose, postprandial glucose, and insulin resistance (measured via the HOMA-IR index)

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Recombinant human insulin-like growth factor-I treatment inhibits gluconeogenesis in a transgenic mouse model of type 2 diabetes mellitus

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