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While both are generally well-tolerated, their safety profiles are distinct

Michael Zezas: So, direction's the same, but the pace and the friction points may vary

The mechanism involves upregulation of matrix metalloproteinases (MMPs) and their inhibitors, which remodel collagen in a more organized way than unassisted healing

In clinical trials, puerarin could also significantly decrease the urinary albumin excretion rate in patients with DKD (Wang et al., 2015a

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It's a watershed move that could unlock a vast new patient population for Novo Nordisk and Eli Lilly and dramatically expand access to medications that were previously out of reach for many people ages 65 and above