Finally, we have seen that the downregulation of HSPB1 , CD44 , and ABCC1 (encoding MRP1) could also contribute to the successful combination of Auranofin with COJEC in NB
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At present, it has been observed that the introduction of glutathione through the routes of administration directly or through the application of patches, are much more effective than the products of oral routes when increasing the level of plasma glutathione, which makes it an instrument of real importance in the hospital environment
A randomized phase III trial evaluated selenium supplementation in selenium-deficient gynecological cancer patients receiving adjuvant radiotherapy, and it proved effective in reducing the incidence of grade 2 diarrhea, particularly in patients with a large planning target volume (387, 388)