For some people, pursuing weight loss can be harmful, for instance by leading to weight cycling or increasing the risk of developing an eating disorder
These drugs mimic the action of the natural GLP-1 hormone, which stimulates insulin secretion, inhibits glucagon release, slows gastric emptying, and reduces appetite
These findings may explain the reduced responsiveness to GIP observed in individuals with T2DM who may have normal or even increased secretion of GIP
However, CagriSema failed to show non-inferiority to tirzepatide after 84 weeks of treatment in a Phase 3 trial comparing the two medicines
Month 3 onward shifts to protein preservation (80-100g daily), gallbladder protection (30-50g healthy fats), and nutrient density since appetite remains suppressed through week 48
How much weight can I lose with Ozempic