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It is metabolically active at rest, contributing meaningfully to basal energy expenditure

Beyond appetite suppression, GLP-1 receptor agonists slow gastric emptying, which prolongs the sensation of fullness after eating

It also plays a role in serotonin synthesis, contributing to emotional resilience

Leucas zeylanica, which is used in traditional medicine for the treatment of GA, can also improve GA inflammation by reducing the metabolite levels through the inhibition of the AA lipoxygenase pathway (225)

Sources Neeland IJ, Linge J, Birkenfeld AL

Stress management: Chronic stress raises cortisol and can trigger overeating