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Finally, we introduce the potential of L-cell differentiation as an attractive future therapeutic approach to increase GLP-1 production as an attractive therapeutic alternative for T2DM

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Not making lifestyle changes during treatment Using GLP-1 medications as the sole weight loss strategy without modifying diet, exercise, sleep, or stress management is like building a house without a foundation

and Garvey WT, Frias JP, Jastreboff AM, le Roux CW, Sattar N, Aizenberg D, Mao H, Zhang S, Ahmad NN, Bunck MC, Benabbad I, Zhang XM

Acute administration of CDCA (chenodeoxycholic acid) also increased GLP-1 secretion in patients with T2DM and healthy control subjects [179]