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E-mail: [email protected] Accepted 6 October 2025 Published 28 October 2025 Conflicts of interest LVK reports financial support from or interest in Teva and Lundbeck

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Ghosh A, et al

Murcia Salud

This creates a vicious cycle where declining NAD+ impairs both PARP-mediated DNA repair and sirtuin-mediated protective gene regulation

The yeast Candida albicans can synthesise carnitine, and while it is not clear whether this is possible in bacteria, they can acquire it from the environment or from metabolic precursors, as it is used in protection against environmental stresses in some species