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August 8, 2022

*In a 72-week study of adults with obesity or overweight (without diabetes), Zepbound showed a clear dose-response curve in mean body weight loss

doi: 10.2337/db09-1694 60 RakipovskiGRolinBNhrJKleweIFrederiksenKSAugustinRet al

Injection technique matters considerably

Why compounded GLP-1s became a multi-billion dollar industry In 2022, demand for Wegovy and Ozempic outstripped what Novo Nordisk could supply

Reconstitution requires an 18-20 gauge draw needle to transfer bacteriostatic water without creating rubber stopper particulate, while injection requires a 29-31 gauge insulin syringe for subcutaneous administration