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Drawing on his research and years in the operating theatre, Alex reflects on the limitations he saw with cemented partial knee replacement and why rethinking fixation could redefine what surgeons and patients come to expect

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Tthe study suggests that loss of glutathione in the affected neurons may impact on energy production in the mitochondria, the power plant of the cells

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In contrast, preoperative GLP-2 plasma concentrations did not differ, but increased 3.4-fold within the first postoperative day in patients with PHLF, compared to an 1.5-times increase in patients who did not develop PHLF, resulting in 2.0-times higher GLP-2 level in PHLF on POD1 ( p = 0.008)