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In vitro , butyrate and propionate also suppress LPS-induced maturation of human monocyte-derived dendritic cells, leading to reduced IL-12 secretion and diminished CD8 + T cell activation (Nastasi et al., 2017)

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If no NADPH is required, ribose-5-phosphate can be made through the nonoxidative phase of the pathway from the conversion of glyceraldehyde 3P and fructose-6P

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