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Instead, the process is flipped: for Wegovy, for example, doses may be reduced in stages from 2.4 mg to 1.7 mg, then to 1.0 mg

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11 A drawback of these medicines has been the necessity to administer them via subcutaneous injection, which limits patient utilization and may reduce opportunities for fixed dose combination treatments with other small-molecule therapies for cardio-metabolic diseases

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