People with digestive conditions such as Crohn's disease, celiac disease, or other inflammatory bowel conditions often have a compromised gut lining and cannot absorb oral B12 efficiently
The data becomes not just invalid, but dangerously misleading
For instance, it has been shown to improve nitrogen absorption, utilization, and insulin secretion, especially in critically ill patients with impaired gastrointestinal absorption due to hypoalbuminemia [2]
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Selected Preclinical Findings NNMT knockdown protects against DIO via increased energy expenditure and remodeled polyamine flux