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MELATONIN SYNTHESIS AND METABOLISM Melatonin Synthesis Melatonin (N-acetyl-5-methoxytryptamine) is synthesized within the pinealocytes from tryptophan, mostly occurring during the dark phase of the day, when there is a major increase in the activity of serotonin-N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT), responsible for the transformation of 5-hydroxytryptamine (5HT, serotonin) to N-acetylserotonin (NAS) (Figure 1)
Reduces the appearance of wrinkles: By boosting collagen and elastin production, GHK-Cu helps reduce the formation of fine lines and wrinkles, giving the skin a smoother, more youthful appearance
Formulated to flush toxins with Glutathione, boost immunity with Vitamin C, increase energy with an extra dose of B12, while also relieving nausea and inflammation
Experimentally-induced hyperthyroidism is associated with activation of the rat hypothalamic-pituitary-adrenal axis
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