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For instance, ripasudil has already been licensed for treating ocular hypertension and open-angle glaucoma, which has potential for rapid translation as a therapeutic to promote hepatocyte engraftment (Table 3)

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FDA scientists recommended against adding all seven to the compounding list, citing inadequate human trials and unresolved questions about contamination, immune reactions and dosing

Skin around the eyes is significantly thinner than other facial areas, has minimal oil glands, and sits close to the sensitive eyeball

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