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Caspase-4/5/11 can also activate the NLRP3 inflammasome, which subsequently activates caspase-1, resulting in the production and release of IL-1 and IL-18 (Sahoo et al., 2023)

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also reported a low risk of hypoglycemia, with events occurring in similar proportions of patients with obesity but without diabetes who were treated with liraglutide 3.0 mg (1.3%) compared with placebo (1.0%) [37]

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