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Need for Regular Medical Supervision: Consistent check-ups are necessary to monitor progress and manage side effects

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Your body will eventually adjust to the medication, the hormonal fluctuations will stabilize, and your fatigue will improve

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Appetite and satiety hormones shift within 24-48 hours of your first dose as GLP-1 receptors activate

When these peptides attach to their respective receptors in the ARC, they activate anorexigenic proopiomelanocortin (POMC) neurons and stimulate POMC processing resulting in -melanocyte-stimulating hormone (-MSH) release [6, 7] leading to satiety, primarily via -MSH-mediated activation of melanocortin 3 and 4 receptors [810]