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Retatrutide in type 2 diabetes: TRANSCEND-T2D-1 Phase 3 results HbA1c 2.0% + weight 16.8% at 40 weeks

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Yes chronic alcohol use (three or more drinks per week) creates baseline suppression of GHRH tone and reduces hepatic IGF-1 production, lowering peptide therapy effectiveness by 3060% over 90 days compared to non-drinkers

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