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35 It has improved steatosis, insulin resistance, and liver stiffness in short-term trials and is actively under clinical investigation as a treatment for MASH

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When Tirzepatide May Be the Better Option Tirzepatide is worth considering if you have more aggressive weight loss goals, if you've plateaued on semaglutide, or if your physician believes the dual GLP-1/GIP mechanism may be more effective for your metabolic profile

The dose is individualized to you rather than factory-set, which is one reason the program uses this format

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A SGLT2i + DPP4i FDC is a suitable option for Indian T2D patients, for the following reasons: Safer, rapid, and sustained glycemic control Improves both insulin resistance and beta cell function Helps reduce body weight and blood pressure (extraglycemic benefits) Reduces pill burden (adherence and compliance improves) Overall cost effective The following decision-making algorithms (Fig