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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.GLP-1 receptor agonists and cardiorenal outcomes in type 2 diabetes: an updated meta-analysis of eight CVOTs

Together, these steps support better glycaemic control and contribute to improved metabolic outcomes

In many cases, employer-sponsored health plans exclude weight-loss medications altogether, even when obesity-related conditions significantly impact overall health outcomes

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In an analysis of more than 100 clinical trials of earlier anti-obesity medications, in studies lasting up to 76 weeks, drug-induced weight loss never exceeded more than nine pounds (4 kg)

In 2025, Novo Nordisk submitted Orforglipron for regulatory review by the FDA, but it is not yet approved