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(PubMed) Carter P, Gray LJ, Troughton J, Khunti K, Davies MJ

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The prevention and treatment of missing data in clinical trials

Patients with high-sensitivity GLP1R variants sometimes tolerate slower dose escalation better, while those with lower-sensitivity versions may achieve results faster with fewer GI complaints

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For example, certain GLP1R variants correlate with differential appetite suppression response, while FTO variants may relate to baseline metabolic risk