Either way, it is often caused by a deficiency in vitamin B12
PLC protein has the biggest size among all PLC family members - 230 kDa and consists of several functional domains including core domain (consisting of EF, X and Y subdomains) which possesses an ability to hydrolyze PIP2, pleckstrin-homology PH and C2 domains, GTP-exchanging (CDC25-like) domain at the C-terminus and two Ras-associating domains at N-terminus [4-6]
Gleber-Netto, Priyadharsini Nagarajan, Xiayu Rao, Shamima Akhter, Tuany Eichwald, Tongxin Xie, Mohammad Balood, Adebayo Adewale, Shorook Naara, Hinduja N Sathishkumar, Islam Shajedul, William McCarthy, Brandi J Mattson, Renata Ferrarotto, Michael K
McBride JT
Metabolism Course Notes
Scientific reports