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There are no major complications

In phase 2 TOPAZ (NCT03921528) and phase 3 SAPPHIRE (NCT05156320) trials, apitegromab treatment improved motor function in patients with spinal muscular atrophy (SMA) 9,16

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On further probing Madsen found that the tumours secreted an abundance of GLP-1, which he published in a paper together with Holst and others in 1995 (Blume, Skouv, Larson)

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Learn more GLP-1 medications like Ozempic and Wegovy are changing how the medical system approaches obesity and metabolic disease