dpp-4 inhibitor and glp-1 receptor agonist combination not recommended guideline Clinical Use of Inhibitors 𝐋𝐚𝐭𝐞𝐬𝐭 𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧 𝐨𝐟 𝐃𝐏𝐏-𝟒 𝐢𝐧𝐡𝐢𝐛𝐢𝐭𝐨𝐫𝐬

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Any comparison of their magnitudes is inference across unlike studies, which cannot establish superiority

These include the following: Medullary carcinoma of thyroid (MTC) and Multiple Endocrine Neoplasia type 2 syndrome (MEN 2): Semaglutide is contraindicated in patients with a personal or family history of thyroid tumors, particularly medullary thyroid carcinoma (MTC) and Multiple Endocrine Neoplasia type 2 syndrome (MEN 2)

AbdolSamad Abedi: Writing original draft (equal)

The evolution of research from identifying single high-impact gene mutations to developing more complex, multi-gene prognostic models based on comprehensive genomic, transcriptomic, and proteomic data signifies a maturation of the field [9, 23,24,25,26]

Understanding Diabetic Acute Kidney Disease and the Role of GLP-1 RAs Diabetic kidney disease (DKD) is a common yet challenging complication of diabetes, often leading to chronic kidney damage, cardiovascular issues, and even end-stage renal disease (ESRD) if left untreated