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Efficacy, safety, and tolerability of oral semaglutide versus placebo added to insulin with or without metformin in patients with type 2 Diabetes: the PIONEER 8 trial

10.1152/ajprenal.00193.2021 116 LuoJ.SunY.LiQ.KongL

Thyroid patients are already at risk of muscle weakness if their levels are not optimal

When multiple symptoms occur simultaneously it can lead many doctors to focus solely on each issue individually instead of looking at what could cause all of these issues to happen at the same time

Study design improvements might include adaptive trial designs that allow dose adjustments based on achieved vitamin D levels, rather than using fixed doses regardless of response