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(By comparison, Novo Nordisks best-seller Wegovy/Ozempic brings in similar multi-billion revenues, but Lillys CAGR in recent quarters has been higher.) Analysts attribute Lillys success to tirzepatides superior weight loss in trials and aggressive marketing

doi: 10.7717/peerj.17891 51 DuanXZhangLLiaoYLinZGuoCLuoSet al

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Improved cardiometabolic profile and glycemic control

The published preclinical work (Neelakantan et al., referenced via PMC5826726) reported clean safety at 20 mg/kg subcutaneous in mice over 11 days

The gradient program at a flow rate of 1 ml/min was as follows: linear gradient from 35-57.5 % B in 10 min, linear gradient from 57.5-67.5 % B in 22 min, linear gradient from 67.5-90 % B in 3 min, isocratic at 90 % B in 5 min, linear gradient from 90-35 % B in 2 min, and isocratic at 35 % B in 5 min