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02Side-effect tolerability Lower dosing typically means a quieter side-effect profile, which makes long-term adherence realistic for the patients who need it most

* Since this piece was published Novo Nordisk has started offering semaglutide at $499 a month for those paying for the drug themselves.

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DDDT Volume 18 , 39253938 (2024)

Since the stomach empties more slowly on GLP-1 meds, patients who continue to eat two or three times a day often overload their gutand get the predictable nausea, bloating, and constipation that can come with that