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How GHK-Cu Is Thought to Work GHK-Cu is thought to work through copper binding, extracellular matrix signaling, fibroblast activity, collagen-related pathways, matrix metalloproteinase regulation, glycosaminoglycan synthesis, and inflammation-related pathways [4], [5], 12
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The permeation rate of GHK-Cu through the stratum corneum seems high, the highest of all three skin strata studied
Key factors include: Goal of use Toxin Clearance and antioxidant support vs