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We do not start at a high dose as you could have an increased risk of side effects such as nausea, diarrhea, constipation, and abdominal pain

There are cases where age advances and the body might find it difficult to assimilate the food ingested due to a natural decline in stomach acid

The silky gel-cream texture absorbs easily for comfortable daily use

Less commonly used today, but still helpful in selected patients with insulin resistance and fatty liver

Their beneficial mechanisms can include the attenuation of neuroinflammation [e.g., valproate via histone deacetylase (HDAC) inhibition in microglia, downregulating interleukin-1 beta (IL-1) and inducible nitric oxide synthase (iNOS)] or the mitigation of glutamatergic excitotoxicity coupled with enhancement of neurotrophic factor expression (e.g., lamotrigine), thereby conferring antidepressant-like potential (Mula and Sander, 2007

10.1136/jitc-2024-008799 47 JiaH.YangH.XiongH.LuoK