2022;34(1):59e7410
The food lists designed for GLP-1 users prioritize easily digestible, protein-rich options that work well even when nothing sounds appetizing
Early human trials with single subcutaneous doses of SAR441255 in healthy subjects demonstrated improved glycemic control during a mixed-meal tolerance test, while also being well-tolerated
The cardinal rule of titration: the timeline is a floor, not a ceiling
Results after 80 weeks showed that individuals on the highest dose lost an average of 28.3% body weight
However, treatment with equimolar doses of GLP1/E markedly improved body weight, food intake, fat mass, leptin levels, glucose metabolism, insulin sensitivity, and circulating insulin levels with far superior efficacy as compared with GLP1 and E monotherapies (Fig