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De Cock VC, Dodet P, Leu-Semenescu S, Aerts C, Castelnovo G, Abril B, et al

The D-retro-inverso design replaces all L-amino acids with D-amino acids and reverses the sequence a structural strategy that preserves the side-chain topology of the original FOXO4 binding region while making the peptide resistant to proteolytic degradation, dramatically extending plasma half-life compared to the natural L-form

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scRNA-seq Growth plates were isolated from the distal femur and proximal tibia of 3-day-old mice (male G6pdh chon+ , n = 1