Although the retro-inverso approach may fail to accurately reproduce biological function in the context of helical structures (e.g., p53 or HIV-1 proteins), certain exceptionssuch as the binding of a p53-derived retro-inverso peptide to its regulator MDM2demonstrate that well-designed D-peptides can, in specific cases, effectively mimic the function of the original peptide
During urgent intraoperative histological examination, the morphological picture was suspicious for a mediastinal cyst and neurinoma with cystic changes
Klotho knockout mice exhibit reduced growth in the context of a early aging phenotype, and histopathological examination of their somatotrophs demonstrate reduced numbers of secretory granules
Clinical studies consistently demonstrate that weight loss in men with obesity typically increases total testosterone levels
Ursini F, Maiorino M, Gregolin C (1985) The selenoenzyme phospholipid hydroperoxide glutathione peroxidase
CAMKII controls the signaling of calcium in cells, which is responsible for the regulation of several cell functions, including apoptosis [195]