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ES031000: 4-Methylumbelliferyl α-N-glycolylneuraminic acid Pack Size:1 mg Fmoc-Thr(β-D-Lac(Ac)7)-OH

SKU: 29211239172

4.4
EUR225.00 EUR245.00

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Description

Fmoc-Thr(β-D-Lac(Ac)7)-OH

The sialic acid carboxyl is protected as a methyl ester to prevent side reactions during synthesis

H-Thr(β-D-GlcNAc)-OH

and the construction of probes for galactose-recognizing proteins

Fmoc-Ser(beta-D-Glc)-OH (Peracetate)

ES031000: 4-Methylumbelliferyl α-N-glycolylneuraminic acid Pack Size:1 mg Fmoc-Thr(β-D-Lac(Ac)7)-OHC21H25NO12 483. 42 A 4 methylumbelliferyl (MU) glycoside of N glycolylneuraminic acid (Neu5Gc), a sialic acid variant carrying an extra hydroxyl on the N acyl group and found in most mammals but not normally in humans. Used as a fluorogenic substrate for sialidases (neuraminidases) with selectivity or preference for Neu5Gc containing sialosides; sialidase catalyzed cleavage of the glycosidic bond releases free Neu5Gc and 4 methylumbelliferone. 4

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