In a forced swimming test, a reduction of the immobility time in bpc 157 (10 microg, 10 ng x kg(-1) i.p.) treated rats corresponds to the activity of the 15 mg or 40 mg (i.p.) of conventional antidepressants, imipramine or nialamide, respectively, given according to the original porsolts protocol
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This period saw an increase in preclinical studies, investigating BPC 157s effects in animal models of injury, inflammation, and disease
Interestingly, some animal studies have explored BPC-157 as a post-surgical adjunct, with promising results in models of tendon-to-bone reattachment
As of 2026, hundreds of rodent studies have been published across multiple research domains