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Synergistic Effect The triple agonism produces metabolic effects larger than any single pathway alone - documented in Jastreboff 2023 Phase II data with 24.2% weight reduction at 48 weeks

1): S124e9

doi: 10.1111/dom.12849 153 WhartonSCalannaSDaviesMDickerDGoldmanBLingvayIet al

Lifestyle Integration While GLP-1 receptor agonists can significantly aid in weight management, they are most effective when combined with a healthy lifestyle

Neuron 70, 908923