However, the FDA label explicitly states that "it is unknown whether GLP-1 receptor agonists cause thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of GLP-1 receptor agonist-induced rodent thyroid C-cell tumors has not been determined." The rodent thyroid has substantially more C-cells than the human thyroid, and rodents may be more susceptible to this effect
In this case, do not jump back in at your previous high dose
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2025;15(2):e70009
Salatzki, J
In addition, non-neuronal cells residing in both the central nervous system (CNS) and peripheral nervous system (PNS) called glial cells, and among them mainly astrocytes, microglia, and oligodendrocytes provide essential metabolic and functional support to neurons, contributing to their plasticity [238,239,240,241]
