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The complex three-dimensional structure required for receptor binding can be disrupted by environmental factors, leading to reduced biological activity

This has not only driven off-label use but also triggered global shortages, affecting diabetic patients who rely on the medication for its approved purpose

No one has bothered to speak up on its behalf and put it firmly into the public domain. (1) - Y

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins