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Compared to the placebo group, patients who took 3 g of immediate-release nicotinic acid daily experienced an average 10% reduction in total blood cholesterol, a 26% decrease in triglycerides, a 27% reduction in recurrent nonfatal myocardial infarction, and a 26% reduction in cerebrovascular events (stroke and transient ischemic attacks)

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Biogerontology (Dordrecht) 26(3):107

Furthermore, lactate enhances transforming growth factor (TGF)- signaling in regulatory T cells (Tregs) through non-histone Kla modifications, exemplified by MOESIN Kla at lysine 72, which subsequently attenuates CD8 + T cell functionality (20, 21)