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After being on ketogenic diet for 4 to 7 months, both patients, a 42-year-old male (patient 1) and a 35-year-old female (patient 2), demonstrated marked increase in absolute GSH levels in both gray matter (0.12 to 1.40 and 0.10 to 0.70 international unit [IU]) and white matter (0.65 to 1.50 and 0.80 to 2.00 IU), as well as at least 50% improvement in seizure duration and frequency (Table 1)

Caregiving strain and allcause mortality: Evidence from the REGARDS Study

L., Smith, B

J Biol Chem 277:4350511 Okamoto T, Akaike T, Sawa T, Miyamoto Y, van der Vliet A, Maeda H (2001) Activation of matrix metalloproteinases by peroxynitrite-induced protein S -glutathiolation via disulfide S -oxide formation

Pharmacol Res 44:491495 [DOI] [PubMed] [Google Scholar] Cadenas E (1989) Biochemistry of oxygen toxicity

Hematol Oncol Clin 23(3):431446 Martin MJ et al (2012) Metformin accelerates the growth of BRAFV600E-driven melanoma by upregulating VEGF-A