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Clinical Eligibility and Provider Oversight Ro Discount requires patients to complete a health questionnaire and be evaluated by a Ro provider (MD or NP)

Because Melanotan II affects pigmentation pathways, it may darken existing freckles or moles and may be associated with new or changing pigmented spots

Be sure to document changes in a simple log or journal too, as this can help you and your clinician spot patterns, address challenges, and adjust strategies as needed

Then we have the ITT data

10.3389/fimmu.2021.741934 88 World Health Organization (2024)

The SURMOUNT-1 trial (N=2,539), which evaluated tirzepatide 5, 10, and 15 mg, reported cholelithiasis in 1.6% of the tirzepatide arm versus 0.5% with placebo over 72 weeks