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Inflammatory bowel disease Inflammatory bowel disease (IBD) is a group of disorders that cause inflammation in the digestive tract, including Crohns disease and ulcerative colitis
TD Cowen analyst Steve Scala has flagged the high rate of discontinuation as a concern and suggested it could make outcomes of future trials harder to predict
Splitting each weekly dose into Monday/Thursday injections reduces peak concentration by ~28%, which may explain reports of reduced nausea
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Nausea, diarrhea, vomiting, and constipation occurred more frequently at higher doses and were mostly mild to moderate in severity
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