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The animal study results are promising enough that it has become one of the most widely self-administered research peptides, but the absence of human trial data means all dosing is extrapolated from animal models adjusted for body weight.

Furthermore, stimulation has recently been shown to be associated with increased neurogenesis in the perilesional cortex, as well as in the mediodorsal and ventrolateral thalamic relay nuclei, providing another mechanism through which the facilitative effects of stimulation may occur

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Remarkably, more than 30 years ago, it was recognized that stimulating adjacent regions of the cerebellar cortexor the stripesresulted in different behavioral outcomes in cerebral palsy patients that showed symptoms of dystonia [140]