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By 2050, almost 60% of adults over 25 are expected to be overweight or obese, up from 29% in 1990, with the biggest growth in sub-Saharan Africa, according to a study in The Lancet External link

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doi:10.1016/j.tins.2025.01.003

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3.1 Inhibition of NRF2 triggers ferroptosis Among the numerous mechanisms that regulate ferroptosis, NRF2 is a significant regulator of the antioxidant system, and its regulation of SLC7A11 has already been discussed

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