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When injected into the brain or the periphery, GIP activates neurons in the hypothalamus 54 , and targeted (DREADD-mediated) activation of hypothalamic GIPR neurons decreases food intake in mice 61

Am J Med Genet B Neuropsychiatr Genet (2006) 141B:94756.10.1002/ajmg.b.30366 23 RoseSMelnykSPavlivOBaiSNickTGFryeREet alEvidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain