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Translation limit Animal and cell findings may not predict human outcomes because metabolism, exposure, receptor expression, administration route, and disease context differ

The body can only absorb approximately 1.5 g per dose through the intrinsic factor mechanism, which is why higher doses rely on passive diffusion for additional absorption

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For a water-soluble vitamin, excreted in sweat and perspiration daily, adequate intake of vitamin B12 is crucial for maintaining overall health and preventing deficiency-related complications